Education

  • B.S., Chemistry, University of Jordan
  • M.S., Chemistry, Mu’tah University
  • Ph.D., Organic Chemistry, Chemnitz University of Technology

Professional Background

  • Postdoctoral Fellow, University of Alberta and National Institute for Nanotechnology
  • Postdoctoral Fellow, University of Alberta and Cross Cancer Institute
  • Assistant Professor, American University of Madaba
  • Associate Professor, American University of Madaba

Certifications

  • Certified to handle Radioactive Materials

Recognition & Awards

  • Awarded certificate for Excellent Achievement by the Dean of Scientific Research and Graduate Studies College, Mu’tah University, 1999
  • DAAD (German Academic Exchange Service) Doctoral Scholarship, 2001-05
  • Scientific Research Support Fund, “Synthesis and Bioassay studies of novel cyclooxygenase-2 inhibitors: Phase One,” 2013-16

Courses Taught

  • General Chemistry I Laboratory
  • Organic Chemistry I
  • Organic Chemistry II
  • Physical Science Laboratory

Publications

  • “Unexpected formation of 1-[4-chloromethylphenyl]-5-[4-(methylsulfonyl)benzyl]-1H-tetrazole and 1-[4-chloromethylphenyl]-5-[4-(aminosulfonyl)phenyl]-1H-tetrazole: Crystal structure, bioassay screening” Baker Jawabrah Al-Hourani, Basem F. Ali, Zaher Judeh, Musa I. El-Barghouthi, Wajdy Al-Awaida, Yasmin Snobar, Fatima El Soubani, Khalid Matalka, Frank Wuest, J. Mol. Struct. 2018, 1164, 317–327.
  • “In vitro anticancer, anti-inflammatory, and antioxidant potentials of Ephedra aphylla” Wajdy Al-Awaida, Baker Jawabrah Al-Hourani, Muhanad Akash, Wamidh H Talib, Sima Zein, Rabah Rashad Falah, J. Cancer Res. Ther. 2017, ahead of print.
  • “Structure-activity relationship of novel series of 1,5-disubstituted tetrazoles as cyclooxygenase-2 inhibitors: Design, synthesis, bioassay screening and molecular docking studies” Baker Jawabrah Al-Hourani, Wajdy Al-Awaida, Khalid Z. Matalka, Musa I. El-Barghouthi, Fatima Alsoubani, Frank Wuest, Bioorg. Med. Chem. Lett. 2016, 26, 4757–4762.
  • “Synthesis and crystal structure of N-[(dimethylamino)methylidene]-4-[1-(4-nitrophenyl)-1H-tetrazol-5-yl]-benzenesulfonamide: Molecular docking and bioassay studies as cyclooxygenase-2 inhibitor” Baker Jawabrah Al-Hourani, Musa I. El-Barghouthi, Robert McDonald, Wajdy Al-Awaida, Sai Kiran Sharma, Frank Wuest, J. Mol. Struct. 2016, 1119, 220–226.
  • “Docking studies and the crystal structure of two tetrazole derivatives: 5-(4-chlorophenyl)-1-{4-(methylsulfonyl)phenyl}-1H-tetrazole and 4-{5-(4-methoxyphenyl)-1H-tetrazol-1-yl}benzenesulfonamide” Baker Jawabrah Al-Hourani, Musa I. El-Barghouthi, Robert McDonald, Wajdy Al-Awaida, Frank Wuest, J. Mol. Struct. 2015, 1101, 21–27.
  • “Synthesis, bioassay studies, and molecular docking of novel 5-substituted 1H tetrazoles as cyclooxygenase-2 (COX-2) inhibitors” Baker Jawabrah Al-Hourani, Sai Kiran Sharma, Jatinder Kaur, and Frank Wuest, Med. Chem. Res. 2015, 28(1), 78–85.
  • “Molecular docking studies and X-ray structure determination of 1-{4-methylsulfonyl)phenyl}-5-phenyl-1H-tetrazole” Baker Jawabrah Al-Hourani, Robert McDonald, Musa I. El-Barghouthi, Wajdy Al-Awaida, Sai Kiran Sharma, Frank Wuest, Jordan J. Chem. 2015, 10(1), 34–40.
  • “Protective role of aqueous medicinal herbal extracts against oxidative stress on Glucose-6-phosphate dehydrogenase activity and RBC fragility” Wajdy Al-Awaida, Muhanad Akash, Baker Jawabrah Al-Hourani, Life Sci. J. 2014, 11(2), 385–391.
  • “Biochemical and hematological indicators of acute and chronic cases of Mediterranean G6PD deficiency patients from southern Jordan” Wajdy Al-Awaida, Muhanad Akash, Baker Jawabrah Al-Hourani, Life Sci. J. 2014, 11(1), 371–377.
  • “Synthesis of unexpected bifunctionalized thiazoles by nucleophilic attack on allenyl isothiocyanate” Baker Jawabrah Al-Hourani, Frank Richter, Kai Vrobel, Klaus Banert, Marcus Korb, Tobias Ruffer, Bernhard Walfort, and Heinrich Lang, Eur. J. Org. Chem. 2014, issue 14, 2899–2906.
  • “Synthesis and evaluation of fluorobenzoylated di- and tripeptides as cyclooxygenase-2 (COX-2) inhibitors” Sai Kiran Sharma, Baker Jawabrah Al-Hourani, Melinda Wuest, Jonathan Y. Mane, Jack Tuszynski, Vickie Baracos, Mavanur Suresh, and Frank Wuest, Bioorg. Med. Chem. 2012, 20, 2221–2226.
  • “Novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors” Baker Jawabrah Al-Hourani, Sai Kiran Sharma, Mavanur Suresh, and Frank Wuest, Bioorg. Med. Chem. Lett. 2012, 22, 2235–2238.
  • “COX-2 inhibitors: A literature review (2009-2010)” Baker Jawabrah Al-Hourani, Sai Kiran Sharma, Mavanur Suresh, and Frank Wuest, Expert Opin. Ther. Pat. 2011, 21, 1339–1432.
  • “Synthesis and evaluation of 1,5-diaryl-tetrazoles as novel cyclooxygenase-2 (COX-2) inhibitors” Baker Jawabrah Al-Hourani, Sai Kiran Sharma, Jonathan Y. Mane, Jack Tuszynski, Vickie Baracos, Torsten Kniess, Mavanur Suresh, Jens Pietzsch, and Frank Wuest,
    Bioorg. Med. Chem. Lett. 2011, 21, 1823–1826.
  • “Synthesis and radiopharmacological evaluation of 18F-labeled peptides for targeting COX-2” Baker Jawabrah Al-Hourani, Sai Kiran Sharma,M Wang, Mavanur Suresh, and Frank Wuest, J. Label. Compd. Radiopharm. 2011, 54, S1.
  • “Synthesis of sulfur-containing aryl and heteroaryl vinyls via Suzuki cross-coupling for the preparation of SERS-active polymers” Rolando Perez-Pineiro, Sheng Dai, Ramon Alvarez-Puebla, James Wigginton, Baker Jawabrah Al-Hourani, and Hicham Fenniri, Tetrahedron Letters 2009, 50, 5467–5469.
  • “Regio- and Stereoselective Synthesis of Thiazole-Substituted Histamine and Adenine Derivatives by Nucleophilic Attack at Allenyl Isothiocyanate” Baker Jawabrah Al-Hourani, Klaus Banert, Tobias Rüffer, Bernhard Walfort, and Heinrich Lang, HETEROCYCLES 2008, 75, 2667–2679.
  • “Synthesis of Functionalized Thiazoles via Attack of Heterocyclic Nucleophiles on Allenyl Isothiocyanates” Baker Jawabrah Al-Hourani, Klaus Banert, Nermeen Gomaa, and Kai Vrobel, Tetrahedron 2008, 64, 5590–5597.
  • “Synthesis and Characterization of Spectroscopically Encoded Nanocomposites” Baker Jawabrah Al-Hourani, Sheng Dai, Ramon A. Alvarez-Puebla, Juan P. Bravo-Vasquez, and Hicham Fenniri, Mater. Res. Soc. Symp. Proc. 2008, 1056, 1056-HH11-32.
  • ”Synthesis and Optical Properties of SERS-active Nanocomposite Microspheres” Abdiaziz A. Farah, Sheng Dai, Baker Jawabrah Al-Hourani, Juan P. Bravo-Vasquez, Jae-Young Cho, and Hicham Fenniri, Mater. Res. Soc. Symp. Proc. 2008, 1024, 1024-A04-03.
  • “Synthesis and characterization of spectroscopically active aryl thioacetyl styrene monomers: Towards a new generation of SERS-active polymers” Baker Jawabrah Al-Hourani, Juan P. Bravo-Vasquez, L. Hermann High and Hicham Fenniri, Tetrahedron Letters 2007, 48, 9144–9147.
  • “Synthesis and Crystal Structure of 2-[1-(5-Methylthiazol-2-yl)-1H-pyrazol-3-yl]-pyridine” Baker Jawabrah Al-Hourani, Klaus Banert, Bernhard Walfort, and Heinrich Lang Anal. Sci. 2006, 22, x275–x276.
  • “Synthesis and Solid-State Structure of 5-Methyl-2-(4-nitroimidazol-1-yl)-thiazole” Baker Jawabrah Al-Hourani, Klaus Banert, Cäcilia Maichle-Mössmer, Adnan Al-Labadi, and Ahmed Abu-Rayyan Anal. Sci. 2006, 22, x107–x108.
  • “Rearrangement Reactions; 14: Synthesis of Functionalized Thiazoles via Attack of Heteroatom Nucleophiles on Allenyl Isothiocyantes” Klaus Banert, Baker Jawabrah Al-Hourani, Stefan Groth, and Kai Vrobel Synthesis 2005, 2920–2926.
  • “The Cycloaddition of Cyclopropenes to Enones” Juma’a R. Al Dulayymi, Mark S. Baird, Helmi H. Hussain, Baker J. Alhourani, Al-Meqdad Y. Alhabashna, Simon J. Coles, and Michael B. Hursthouse, Tetrahedron Letters 2000, 41, 4205–4208.

Presentations

  • Building International Networks for Enhancement of Research in Jordan Humboldt Kolleg 2014: “Molecular docking studies and X-ray structure determination of 1-{4-methylsulfonyl)phenyl}-5-phenyl-1H-tetrazole” Baker Jawabrah Al-Hourani, Robert McDonald, Musa I. El-Barghouthi, Wajdy Al-Awaida, Sai Kiran Sharma, Frank Wuest, Amman, Jordan. April 3-5, 2014.
  • 19th International Symposium on Radiopharmaceutical Sciences (ISRS) 2011: “Synthesis and radiopharmacological evaluation of 18F-labeled peptides for targeting COX-2” Baker Jawabrah Al-Hourani, SaiKiran Sharma, M Wang, Mavanur Suresh, and Frank Wuest, Amsterdam, Netherlands. Aug 28-Sep 2, 2011.
  • 93rd Canadian Chemistry Conference and Exhibition (CSC) 2010: “Synthesis And Evaluation of 1,5-Diaryl-Tetrazoles As Novel
    Cyclooxygenase-2 (COX-2) Inhibitors” Baker Jawabrah Al-Hourani, Sai Kiran Sharma, Mavanur Suresh, and Frank Wuest, Toronto-Ontario, Canada, May 29th-June 2nd 2010.
  • 91st Canadian Chemistry Conference and Exhibition (CSC) 2008: “A New Methodology for the Synthesis of Spectroscopically Active Thioacetyl Styrene Monomers” Baker Jawabrah Al-Hourani, Juan P. Bravo-Vasquez, L. Hermann High, Hicham Fenniri, Edmonton-Alberta, Canada, May 24-28, 2008.
  • MRS 2007: “Synthesis and characterization of spectroscopically encoded nanocomposites” Baker Jawabrah Al-Hourani, Sheng Dai, Ramon A. Alvarez-Puebla, Juan P. Bravo-Vasquez, and Hicham Fenniri, Boston, USA.